Cillian Murphy
Getty ImagesOppenheimer is Cillian Murphy’s first starring role in a Christopher Nolan film, though they have collaborated on five other earlier movies. The pair reportedly first met to see if Murphy would be a good fit to play Bruce Wayne/Batman in Batman Begins, but he was instead offered the role of the iconic villain Scarecrow. Murphy took home the trophy for Best Actor in a Motion Picture - Drama at the 2024 Golden Globes for his performance.
J. Robert Oppeneimer
Getty ImagesMurphy plays the movie’s namesake, J. Robert Oppenheimer. His scientific expertise was pivotal in the development of the atomic bomb as the director of the Manhattan Project’s Los Alamos Laboratory in New Mexico. After developing the technology, Oppenheimer became an advocate for the international control of nuclear power to avoid further proliferation and opposed the development of the second-generation nuclear bomb design: the hydrogen bomb.
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Emily Blunt
Getty ImagesEmily Blunt stars in her first Christopher Nolan film with this part. The actor has a ton of range and can hold her own in a period drama, fantasy world, or elaborate science-fiction scenario. In this interview with People, Blunt recalled that the vibe on the set was “like being at camp!"”
Katherine “Kitty” Oppenheimer
Getty ImagesBlunt plays Kitty Oppenheimer (née Katherine Puening), a biologist who met Robert in 1939 while completing postgraduate research at UCLA and married to her third husband, Stewart Harrison. After marrying Robert in 1940, Kitty lived at the Los Alamos facility with her new husband and their children. Her biological expertise also came in use as she helped health workers at Los Alamos assess the effect of radiation on participants’ blood.
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Matt Damon
Getty ImagesActor-director-writer Matt Damon has worked with Nolan once before on Interstellar as Mann, an astronaut the main crew discovers in cryosleep on a mysterious frozen planet. Along with doing great acting work recently, he was one of the screenwriters of Ridley Scott’s The Last Duel with Ben Affleck and Nicole Holofcener.
Lieutenant General Leslie Groves
Getty ImagesDamon plays U.S. Army Corps of Engineers officer Lieutenant General Leslie Groves. After overseeing the construction of the Pentagon, Groves became a director of the Manhattan Project, helping select research sites, secure materials, and construct facilities needed by the scientists. As one of the military leads of the project, he was also in charge of intelligence regarding Germany’s nuclear weapons project and helped select the Japanese cities Hiroshima and Nagasaki as targets for the United States’ deadly nuke attacks.
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Florence Pugh
Getty ImagesFlorence Pugh had a strong 2022 with The Wonder and Don’t Worry Darling, and one of her most memorable roles was as Amy in 2019’s Little Women. The performance earned her an Oscar nomination. Oppenheimer is her major project for this year, but look for her appearance in Dune: Part Two come 2024.
Jean Tatlock
Public DomainPugh plays Jean Tatlock, an American psychiatrist who had a romantic relationship with Oppenheimer before he married Kitty, which also rekindled during the marriage. Tatlock also introduced Oppenheimer to several Communist Party associates or sympathetic groups during their initial relationship in California.
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Robert Downey Jr.
Getty ImagesRobert Downey Jr. took a brief break from acting after leaving the role of Tony Stark/Iron Man in the MCU, but he’s back in a big way with this film. He was an awesome movie superhero but has also played classic characters like Sherlock Holmes, and even has an Oscar-nominated performance as Charlie Chaplin under his belt. His Oppenheimer role has earned him flowers as well: Downey Jr. accepted the trophy for Best Supporting Actor in Any Motion Picture at the 2024 Golden Globes.
Lewis Strauss
Getty ImagesDowney plays former Atomic Energy Board (AEC) chairman Lewis Strauss. Strauss served in the U.S. Navy Reserve during WWII, and he was reportedly frustrated over the secrecy of the Manhattan Project. Strauss joined the AEC in 1947 and had a lot of influence over America’s nuclear strategy during the early Cold War. He distrusted Oppenheimer due to the physicist’s Communist beliefs and was the driving force of the 1954 AEC Personnel Security Board hearings that led to Oppenheimer’s security clearance being revoked.
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Josh Hartnett
Getty ImagesJosh Hartnett has historical film experience from Michael Bay’s Pearl Harbor, and this is certainly a pretty different approach to the similar time period. He has more recently appeared in films like Operation Fortune: Ruse de Guerre, and shows like Penny Dreadful as well as an episode of the new Black Mirror season.
Ernest Orlando Lawrence
Getty ImagesHartnett plays Ernest O. Lawrence, a nuclear physicist known as the inventor of the particle accelerator the cyclotron. His expertise in these machines brought him into the fold of the military during WWII, and his work on uranium-isotope separation advanced the development of the atomic bomb.
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Rami Malek
Getty ImagesRami Malek is fresh off wrapping up his incredible role as Elliot in Mr. Robot in 2019, as well as his Oscar-winning portrayal of Freddie Mercury for Bohemian Rhapsody.
David Hill (Left)
Getty ImagesMalek plays physicist David L. Hill, who worked on the Manhattan Project at the University of Chicago’s Metallurgical “Met” Lab. He was a signee of the Szilard Petition, a memo signed by 70 scientists and other workers calling on President Harry S. Truman to perform a demonstration of the nukes for Japan instead of dropping them on cities.
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Kenneth Branagh
Getty ImagesThis will be Kenneth Branagh’s third film with Nolan, and he is also a world-renowned actor-director with credits from excellent Shakespeare adaptations like Henry V, one of the first modern MCU films with Thor, and the recent Oscar-winning film Belfast.
Niels Bohr
Getty ImagesBranagh plays Niels Bohr, the renowned physicist who developed the Bohr model of the atom. He occasionally visited the Los Alamos Lab to consult on a few issues with the Manhattan Project and became an advocate for international cooperation on the development of nuclear energy late in life.
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Benny Safdie
Getty ImagesBenny Safdie exploded on the scene along with his brother Josh with their films Heaven Can Wait, Good Time, and Uncut Gems. Along with co-directing these movies, Safdie had a main role in Good Time and has acted in other projects like Licorice Pizza and Stars at Noon.
Edward Teller
Getty ImagesSafdie plays Edward Teller, a Hungarian-American physicist who was an early Manhattan Project contributor. He gave a controversial testimony in Oppenheimer’s AEC trial, where he referred to his former superior’s actions as “confused and complicated” and supported the removal of his security clearance.
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Dylan Arnold
Getty ImagesDylan Arnold has made a name for himself in dramas like Mudbound, joined an iconic horror franchise with Halloween Kills, and now in his first Christopher Nolan movie.
Frank Oppenheimer
Getty ImagesArnold plays Frank Oppenheimer, the younger brother of Robert who followed in his footsteps to become a physicist as well. He began working at Los Alamos in 1943, with responsibilities regarding uranium enrichment among others. His membership to the American Communist party was scrutinized in the late ’40s, causing him to be blacklisted from any scientist or professor jobs for several years during the height of McCarthyism.

Jacob is a Temporary Partnerships Editor at Hearst based in Queens, New York with his partner and cat Tiger. He loves learning and writing about Film and TV, Video Games, and the weird histories of unexpected subjects.
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