Infamous drug trafficker Griselda Blanco is suspected of committing more than 200 murders while transporting cocaine from Colombia to the U.S. She was murdered in Colombia in 2012.

Richard "The Iceman" Kuklinski parlayed his penchant for violence into a hitman contract for some of the most prominent Mafia crime families, and is believed to have killed between 100-200 men.

A child from an Italian immigrant family, Al Capone, also known as "Scarface," rose to infamy as the leader of the Chicago Outfit, an organized crime syndicate during the Prohibition era.

Henry Hill was a member of the Lucchese crime family who became a federal informant, inspiring the Martin Scorsese movie 'Goodfellas.'

Gangster Dutch Schultz built up a criminal network that included bootlegging, illegal gambling and murder. His biggest enemies were Legs Diamond and the IRS.

Jesse James was a bank and train robber in the American Old West, best known as the leading member of the James-Younger gang of outlaws.

The two-night docuseries event, 'GOTTI: Godfather & Son,' tells the story of the legendary Gambino crime family through the intimate and complicated relationship between John Gotti Sr. and his son, John Gotti Jr. Airs Saturday & Sunday at 10/9c on A&E.

Mickey Cohen became the West Coast racket boss in 1947, after his mentor and predecessor, Bugsy Siegel, was assassinated.

Whitey Bulger was a prominent figure in Boston's organized crime scene from the 1970s until the mid-'90s, when he fled the area. Captured in 2011, he was later found guilty of federal racketeering, extortion, conspiracy and 11 murders.

Stephanie St. Clair battled Dutch Schultz for control of her criminal empire in Harlem in the 1930s.

Joaquín Guzmán Loera, aka "El Chapo," is a Mexican drug lord who was head of the Sinaloa cartel, the world's most powerful drug-trafficking organization.

Carlos Marcello was best known as the mob boss of New Orleans, and for the FBI's investigation of his possible involvement in JFK's assassination.

Known as "The Irishman," Danny Greene was one of most notorious crime figures in the Midwest. He even took on the entire mafia in his quest for power.

Larry Hoover, also known as "King Larry," is the notorious former leader of the Black Gangster Disciple Nation, a Chicago street gang that spread nationwide.

Arnold Rothstein was a Jewish-American mob boss who inspired a character in 'The Great Gatsby' and was portrayed in the HBO series 'Boardwalk Empire.'

Meyer Lansky, an organized-crime figure known for his sharp financial acumen, was instrumental in the development of a national crime syndicate in the United States.

Lucky Luciano was an Italian-born American mobster best known for engineering the structure of modern organized crime in the United States.

New York gangster Joe Gallo was both a hero and villain; a very public criminal who hung out with pop stars and was immortalized in the Bob Dylan song, Joey.

Tony Spilotro is best known as a ruthless Chicago mob representative in Las Vegas from the 1970s to the '80s. He was brutally beaten and murdered by other mobsters in 1986.

Drug kingpin Guy Fisher was a member of Nicky Barnes' heroin enterprise, The Council, and helped renovate the Apollo Theater.

Tony 'Big Tuna' Accardo turned to a life of crime in his early teens, and quickly rose to infamy as a soldier in Al Capone's Chicago Crime Syndicate.

Iconic mobster Benjamin "Bugsy" Siegel built the Flamingo casino in Las Vegas, igniting an era of glamour, gambling and gangsters in the desert.

John Dillinger was an infamous gangster and bank robber during the Great Depression. He was known as "Jackrabbit" and "Public Enemy No. 1."