Frederick Loewe, along with collaborator Alan Jay Learner, composed several Broadway scores, including the now-famous songs in My Fair Lady.

• Songwriter
  (1901–1988)

Frederick Sanger received the Nobel Prize in Chemistry twice. He discovered the structure of insulin and researched of DNA molecule sequencing.

• Scientist, Chemist
  (1918–2013)

Frederick Fleet was a crewman and lookout on the RMS Titanic. Fleet was one of the first to spot the iceberg that sunk the Titanic on April 15, 1912, and was one of the 705 passengers to survive the disaster.

• (1887–1965)

Frederick II, known as Frederick the Great, was Prussia's king from 1740 to 1786. By winning wars and expanding territories, he established Prussia as a strong military power.

• King
  (1712–1786)

Famed 19th-century author and orator Frederick Douglass was an eminent human rights leader in the anti-slavery movement and the first African-American citizen to hold a high U.S. government rank.

• Journalist, Civil Rights Activist, Author, Government Official
  (c. 1818–1895)

Musician Frederick "Toots" Hibbert helped define reggae with his band Toots and the Maytals. Their 2004 album, True Love, won a Grammy in 2005.

• Songwriter, Singer
  (c. 1946–)

Frederick Jones was an inventor best known for the development of refrigeration equipment used to transport food and blood during World War II.

• Inventor
  (1893–1961)

Empress Frederick was the oldest child of Queen Victoria and Prince Albert of England. She married the future German emperor, Frederick III, in 1858, thus becoming empress of Germany and queen of Prussia.

• Queen, Emperor
  (1840–1901)