Among the known and apparent companions of the artist are several recognizable names, including Leon Trotsky and Georgia O'Keeffe.

The confidants and collaborators navigated the '60s and '70s together, rising to the top of their fields.

The actress and playwright were once enamored with each other — even writing love letters — but their relationship wasn't strong enough to endure.

The Material Girl's mom passed away from cancer when the singer was five years old.

Smiling on the outside, the famed duo's connection was even deeper, more complex and more fraught than their public image suggested.

In 1969, when black Americans were still prevented from swimming alongside whites, an episode of 'Mister Rogers' Neighborhood' broke the color barrier.

The 'Charlie and the Chocolate Factory' author found it hard to go on after his daughter Olivia's sudden death.

After the comedian received his first ventriloquist's doll, he began to teach himself the skill of ventriloquism through dedicated study and practice.

'Phone Call to God' put the comedienne on the map — and on Johnny Carson's famed couch.

Through laughter and tears, the comedian and 'Superman' star maintained a brotherly bond.

The comedienne and royal may appear to be unlikely pals, but the two shared a close relationship that endured until Rivers' death in 2014.

Titanic survivor Elsie Bowerman went on to participate in and witness major historical events; she also got to experience the broader opportunities for women in the 20th century.

The first lady overcame political objections and a lack of funds to embark upon a sweeping restoration of the White House that covered every presidential era and enthralled the country.

The first lady continued to wear the outfit covered in her husband's blood to convey a message and as a way of coping with her own trauma.

After the terrorist attacks in September 2001, Fred Rogers offered heartfelt words of hope and recovery.

The rapper's professional and personal life was at an all-time high when he was gunned down in September 1996.

Before he began sharing his love of landscapes with audiences on 'The Joy of Painting,' the artist spent 20 years of his life in the U.S. Air Force.

Gypsy Rose Blanchard's mother, Dee Dee, falsely claimed her daughter was suffering from different illnesses until Gypsy arranged for her boyfriend to kill her mother in 2015.

There many similarities between actress the character Hepburn famously portrayed in the 1961 film 'Breakfast at Tiffany's.'

The Miami estate was a luxurious home that showcased his creative vision — and also the same place where he was shot to death.

The singer's last month featured positive personal and professional developments, but also included several confrontations with the woman who would become her killer.

Queen Elizabeth II's younger sister led a charmed life as a member of the British royal family but was unlucky in love.

Princess Margaret was a royal rebel who followed a different path in life than her sister, who ascended the throne.

The 1961 visit demonstrated that although Queen Elizabeth's powers were limited, by wielding those powers well, the monarchy could still have an impact.