The president and first lady's romance endured Hollywood, politics and personal tragedies.

Winning the first season of the reality show made her a household name and launched her career on a path that includes Grammy and Emmy wins, as well as a successful talk show.

Fans of the hit sitcom were scratching their heads at the beginning of season six when a new actor stepped into the role of Darrin.

Though he only released one film before his dying in a car crash, the actor became a lasting figure in pop culture.

Lansbury was a stage and screen star, and her decision to transition to television was a big career gamble.

The ‘Star Wars’ heroine and the singer-songwriter of Simon & Garfunkel fame connected right away, but their subsequent relationship was often rocky.

During the time of the kiss, there were still many questions about AIDS, a disease which Hudson had, including if you could transmit it from locking lips.

Reynolds and Fisher were in a seemingly happy marriage with two children until he blindsided the actress and left her for her best friend, Taylor.

Though briefly married, the Hollywood icon and Yankees superstar forged a bond that he held onto tightly, even after her tragic death.

In the 1980s, the actress was at the top of her career, but she traded it in for a family-oriented life in the capital with her Washington-insider husband.

The "Guess Who's Coming to Dinner" costars spent more than two decades hiding their status from the public.

After Clapton's 4-year-old son accidentally fell out of a window to his death, the musician turned his grief into the heart-wrenching ballad.

The twice-married actors met when Wood was just a child star and endured a rollercoaster romance until her mysterious death.

Hollywood took some liberties while bringing the story of this musical Austrian family to the big screen.

After showing up to the set intoxicated, director Mike Nichols made the actress pay $80,000 to compensate for the production time lost.

While recording the 1977 album, professionally, the band was on top, but personally, things were falling apart.

When the then-29-year-old pitched the TV show to network execs, he described it as “a comedy show, frank and intelligent, for young, urban adults.”

The NFL star received a life sentence in 2015 for the murder of his friend Odin Lloyd. He hung himself in his jail cell two years later.

As Benedict's successor, Francis' liberal and minimalistic beliefs are a stark contrast from Benedict's more traditional practices.

The "I Love Lucy" actors had instant chemistry, but often struggled during their 20-year marriage.

Theories of mafia involvement have made headlines since the president's November 22, 1963 assassination.

After a deal went sour, the automotive brands went head-to-head at Le Mans in 1966.

Immediately drawn to each other, the country singers navigated rocky roads before and throughout their marriage.

The reigning king and queen of country music met as struggling unknowns. Decades later they would wed as world-famous entertainers.