Family Ties, 1982-89
Meredith Baxter
Character: "Elyse Keaton"
Family: Michael, Alex, Mallory, Jennifer, Andy

The Cosby Show, 1984-92
Phylicia Rashad
Character: "Claire Huxtable"
Family: Cliff, Theo, Sandra, Denise, Vannessa, Rudy

Roseanne, 1988-97
Roseanne
Character: "Roseanne Conner"
Family: Dan, Becky, Darlene, DJ

The Simpsons, 1989-
Julie Kavner
Character: "Marge Simpson"
Family: Homer, Bart, Lisa, Maggie

Kate and Allie, 1984-89
Susan St. James
Character: "Kate Mcardle"
Family: Emma

Kate and Allie, 1984-89
Jane Curtin
Character: "Allison Lowell"
Family: Charles, Chip, Jenny

Who's the Boss, 1984-92
Judith Light
Character: "Angela Bower"
Family: Tony, Mona, Jonathon, Samantha

Growing Pains, 1985-92
Joanna Kerns
Character: "Maggie Seaver"
Family: Jason, Mike, Carol, Ben

Married with Chlidren, 1987-97
Katey Sagal
Character: "Peg Bundy"
Family: Al, Kelly, Bud

Murphy Brown, 1988-98
Candice Bergen
Character: "Murphy Brown"
Family: Avery

The Wonder Years, 1988-93
Alley Mills
Character: "Norma Arnold"
Family: Jack, Kevin, Karen

Family Matters 1989-98
Jomarie Payton
Character: "Harriet Winslow"
Family: Carl, Eddie, Laura, Steve