I Love Lucy, 1951-57
Lucille Ball
Character: "Lucy Ricardo"
Family: Ricky, Little Ricky

The Adventures of Ozzie & Harriet, 1952-66
Harriet Hilliard
Character: "Harriet Nelson"
Family: Ozzie, David, Ricky

Father Knows Best, 1954-60
Jane Wyatt
Character: "Margaret Anderson"
Family: Jim, Bud, Betty, Kathy

Leave it to Beaver, 1957-63
Barbara Billingsly
Character: "June Cleaver"
Family: Ward, Theodore, Wally

The Donna Reed Show, 1958-66
Donna Reed
Character: "Donna Stone"
Family: Alex, Jeff, Mary