Madeleine Albright became the first woman to represent the U.S. in regards to foreign affairs as the secretary of state.
One of America's most beloved comedians, Lucille Ball is particularly known for her iconic TV show I Love Lucy.
Abigail Breslin is one of the youngest actresses to receive an Academy Award for Best Supporting Actress for her role in the film Little Miss Sunshine.
Laura Bush is the wife of 43rd U.S. President George W. Bush. She served as first lady from 2001 to 2009.
With hits such as "Vision of Love" and "I Don't Wanna Cry," pop diva Mariah Carey holds the record for most No. 1 debuts in Billboard Hot 100 history.
Chelsea Clinton is a media correspondent and activist who is the daughter of Hillary Rodham Clinton and Bill Clinton.
When Hillary Clinton was elected to the U.S. Senate in 2001, she became the only American first lady to hold national office. She became the 67th U.S. secretary of state in 2009, serving until 2013.
Television journalist Katie Couric, formerly of the Today show, signed a deal with CBS in 2006 to become the first woman to anchor CBS Evening News alone.
Singer-songwriter Sheryl Crow sang backup for stars like Rod Stewart before becoming a star in own right. Her 1996 album Sheryl Crow won two Grammys.
Sandra Dee became the “Queen of Teens” in 1950s Hollywood, appearing in such films as Gidget and A Summer Place.
African American poet Rita Dove is the youngest person and the first African American to be appointed Consultant in Poetry at the Library of Congress.
Figure skater Peggy Fleming won the only U.S. gold medal in the 1968 Olympics. Later, she publicly battled breast cancer, beating it with radiation therapy.
Photographer and activist Tipper Gore, wife of Vice President Al Gore, co-founded the Parents' Music Resource Center, and was Clinton’s mental health advisor.
Doctor Mae C. Jemison is the first African-American woman ever to be a U.S. astronaut. In 1992, she flew into space aboard the Endeavour.
Star Jones is a lawyer and television personality best known for co-hosting ABC's The View from 1997 until 2006.
One of the greatest athletes of all time, track and field star Jackie Joyner-Kersee has won three Olympic gold medals, as well as one silver and two bronze.
Ethel Kennedy is best known as the widow of Robert F. Kennedy, the former U.S. Attorney General and New York Senator who was assassinated in 1968.
Professional golfer Nancy Lopez was named Player of the Year four times during her career. She was the first woman to be awarded the Frances Ouimet Award.
Susan Lucci is an American actress, best known for portraying Erica Kane on the daytime drama All My Children.
Abby Lee Miller, who runs a Pittsburgh dance studio, is known for her tirades and tough training as star of Lifetime TV's reality show Dance Moms.
In the 1980s, Jessye Norman’s roles in Aïda and Les Troyen made her one of the most popular and highest paid soprano opera singers worldwide.
Sandra Day O'Connor was the first woman appointed to the U.S. Supreme Court. A Republican, she was considered a moderate conservative and served for 24 years.
Jane Pauley was a correspondent and co-anchor for NBC’s Today. She also started the weekly magazine series Real Life with Jane Pauley, later renamed Dateline.
Nancy Reagan is a former first lady of the United States, the widow of Ronald Reagan, who founded the "Just Say No" drug awareness campaign.
Janet Reno broke new ground in 1993 as the first woman to serve as U.S. Attorney General, serving under President Bill Clinton.
Known for her boundless energy and pert demeanor, Reynolds' most memorable turn was in the 1952 musical Singin' in the Rain.
Condoleezza Rice is the first black woman to serve as the United States' national security adviser, as well as the first black woman to serve as U.S. Secretary of State (2005-09).
In 1983, astronaut and astrophysicist Sally Ride became the first American woman in space aboard the space shuttle Challenger. Ride died on July 23, 2012 at the age of 61, following a battle with pancreatic cancer.
Social activist, writer, editor, and lecturer Gloria Steinem has been an outspoken champion of women's rights since the late 1960s.
Martha Stewart is an American media mogul best known for her television show and magazine, Martha Stewart Living.
Singer/songwriter Taylor Swift is one of country music's top recording artists, having crossed over into pop and winning many awards.
Shirley Temple was the leading child actor of her time, receiving a special Oscar and starring in films like Bright Eyes and Heidi.
All-American model Cheryl Tiegs appeared in numerous photo shoots with high profile magazines like Vogue, Elle, and Sports Illustrated, in the 1970s.
Mary Tyler Moore is an Emmy and Tony Award-winning actress and television star know for her roles on The Dick Van Dyke Show and The Mary Tyler Moore Show.
TV Journalist Barbara Walters was on the Today show for 11 years. She is also the first woman to co-anchor a network (ABC) evening news program.
Soul singer Warwick became a superstar with early hits like "Walk On By" and "I Say a Little Prayer," and later with albums like Dionne and Heartbreaker.
Venus Williams rose from a tough childhood in Compton, Los Angeles to become a champion women's tennis player and four-time Olympic gold medalist.