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Explorer, navigator, Columbus was born in 1451, in the Republic of Genoa (Italy) to the son of a weaver. Columbus first went to sea as a teenager, participating in several trading voyages in the Mediterranean and Aegean seas. One such voyage, to the island of Khios, in modern day Greece, brought him the closest he would come to Asia.

His first voyage into the Atlantic Ocean in 1476 nearly cost him his life as the commercial fleet he was sailing with was attacked by French privateers off the coast of Portugal. His ship was burned and Columbus had to swim to the Portuguese shore and make his way to Lisbon, Portugal, where he eventually settled and married Felipa Perestrello. The couple had one son, Diego in about 1480. His wife died soon after and Columbus moved to Spain. He had a second son Fernando who was born out of wedlock in 1488 with Beatriz Enriquez de Arana.

Columbus participated in several other expeditions to Africa gaining knowledge of the Atlantic currents flowing east and west from the Canary Islands. Muslim domination of the trade routes through the Middle East makes travel to India and China difficult. Believing a route sailing west across the Atlantic would be quicker and safer, Columbus devised a plan to sail west to get reach the East. He estimated the earth to be a sphere approximately 63% its actual size and the distance between the Canary Islands and Japan to be about 2,300 miles. Many contemporary nautical experts disagreed, adhering to the second century BC estimate of the earth's circumference at 25,000 miles. This made the distance between the Canary Islands and Japan about 12,200 statute miles. While experts disagreed with Columbus on matters of distance, they concurred that a westward voyage from Europe would be an uninterrupted water route.

Rejected by the Portuguese king for a three-ship voyage of discovery, Columbus took his plan first to Genoa and then to Venice but was rejected there too. He then went to the Spanish monarchy of Isabella of Castille and Ferdinand of Aragon, in 1486. Their nautical experts too were skeptical and initially, Columbus was rejected. The idea however, must have intrigued the monarchs, for they kept Columbus on a retainer. But their focus was on a war with the Muslims and Columbus would have to wait.