In Miami Sgt. Altarr Williams and detective Frankie Sanchez investigate the murder of Darrell Harrell, gunned down for trying to push a group of drug dealers out of Overtown. Months pass without a lead as the team tries everything they can to keep the case from going cold. Meanwhile in Harris County, Texas, Sgt. Craig Clopton works the murder of Virgil Fuselier, found stabbed to death in his apartment. As Clopton begins the investigation he finds trail of clues that may trace back to the killer.

In Charlotte, when a store clerk and father of three young children is shot in a robbery by a masked man, lead Detective David Osorio and his team interview witnesses and find that no one knows the shooter. With little to go on, Osorio must find a way to identify his suspect before he can hope to track him down. And in Miami, lead Detective Kevin Ruggiero and his team head to Overtown to investigate the murder of a young father shot in the street. When Ruggiero learns that the victim's friends are out to retaliate, he must race to find the shooter before there's another killing.

In Miami, two men are found beaten and shot behind an abandoned house. As Det. TC Cepero digs deeper into the case he unearths more than one reason the men could have been killed.